Something I needed to do due to problems - delete messages in the queue:
/usr/local/sbin/qmail stop
find /var/qmail/queue/mess -type f -exec rm {} \;
find /var/qmail/queue/info -type f -exec rm {} \;
find /var/qmail/queue/local -type f -exec rm {} \;
find /var/qmail/queue/intd -type f -exec rm {} \;
find /var/qmail/queue/todo -type f -exec rm {} \;
find /var/qmail/queue/remote -type f -exec rm {} \;
/usr/local/sbin/qmail start
